IVF in IRAN
In Vitro Fertilization also known as IVF which was first performed in 1978, and has become the standard for treating many fertility disorders. The first IVF Iranian baby was born in 1990 in Yazd city and Iran made great progress in line with world knowledge. Today, Iran is one of the most successful countries in the world using IVF.
With over 30 years of experience in infertility research and treatment, Iran is one of the world’s pioneers in effective infertility treatment. There are more than 80 specialized fertility clinics in Tehran, Urmia, Yazd, Isfahan and other cities of Iran. These clinics with the up-date of knowledge and equipment in the world; offer the various methods for infertility treatments with the best quality.
The high quality and low cost of infertility treatments in Iran have led many medical tourists to choose this destination for the treatment of their infertility problems.
For more information about IVF in Iran, you can contact us.
What is IVF?
In vitro fertilization (IVF) is one of the assisted reproductive techniques (ART) which a man’s sperm and the woman’s egg are combined in a laboratory dish, where fertilization occurs. When the egg is fertilized, the primary cell begins to divide and form the embryo. The resulting embryo or embryos is/are then transferred to the woman’s uterus to implant and develop naturally.
When is IVF recommended?
Nowadays, IVF can be used to treat infertility with various causes:
- Blocked of one or two female uterine tubes.
- Male factor infertility including decreased sperm count or sperm motility,and abnormal shape of sperm
- Severe ovarian dysfunction
- Ovarian failure and reduced female ovarian reserve for some reasons such as premature menopause or cancer, etc.
- unexplained infertility
- Couples with Multi factorial Infertility factors
- Couples with the failed infertility treatments such as IUI
How is IVF done?
IVF (in Vitro Fertilization) is a common procedure, used to overcome a range of fertility issues. It is a multi-step process involving ovulation induction, egg retrieval, fertilization, culture, and embryo transfer. The IVF process can be explained in these four steps:
Fertility medications are prescribed to control the timing of the egg ripening and to increase the chance of collecting multiple eggs during one of the woman’s cycles. These drugs are used to stimulate the growth of several eggs in the ovaries. Normally, only one egg grows per month. However, during the IVF treatment process, several eggs are needed. Because, after the fertilization phase, some eggs will not fertilize or they will not grow naturally. Induction ovulation drugs start from 8 to 14 days before the menstruation and you should see your doctor every two or three days to check the ovulation condition. Depending on the case, normally the ovulation Induction procedure takes 10 to 20 days.
Ovum Pick up:
After the induction ovulation and development of suitable oocytes for fertility, the eggs should be retrieved for in vitro fertilization. Egg retrieval or egg ‘pick up’ is a hospital day procedure where the eggs are collected from your ovaries. An anesthetist will get you ready for a general anesthetic. Your fertility specialist uses the latest ultrasound technology to guide a needle into each ovary and inserts a very thin needle through the upper vaginal wall and removes fluid, which contains eggs, from the follicles of the ovaries. The average number of eggs collected is 8-15. The procedure usually takes less than 30 minutes.
Fertilization and embryo culture:
After the ovum picks up, the embryologist examines the obtained egg to select mature eggs that are suitable for fertilization.
The mature eggs are placed in a culture medium and the sperm transferred to an incubator for fertilization. In IVF, high-motility sperms move to the eggs and fertilize them. Once this occurs, the fertilized eggs are considered embryos.
In condition with the low number and low quality of sperm, the specialist uses intracytoplasmic sperm injection (ICSI). It is as an additional part of an IVF treatment cycle which a single sperm is injected into each egg to assist fertilization. If each egg is fertilized, the resulting cell begins to divide and reaches about 10 cells in 3 days. Finally, the embryo is transferred to the uterus within 2 to 5 days after fertilization.
- Embryo Transfer
An embryo transfer is the last part of the in vitro fertilization (IVF) process. Around 2 or 3 days before the embryo transfer, the doctor will choose the best eggs to transfer to the uterus. Sometimes, there are “extra” embryos after an IVF cycle, and most people choose to freeze or cryopreserve their extra embryos. Embryo transfer is a simple procedure that does not require any anesthesia. Embryos are loaded in a soft catheter and are placed in the uterine cavity through the cervix. The procedure is usually painless, but some women experience mild cramping.
IVF Successful Rate
Two weeks after the IVF procedure, if the pregnancy test was positive, it shows the process is successful. The study shows that the female under 35 years old, has over 40% chance of pregnancy. By increasing age, the chance of pregnancy will be reduced. The success rates are generally reported accordingly to the woman’s age since as a woman gets older, the IVF success rates go down. In spite of the female age, the couple’s lifestyle is an important factor in IVF success. Also, smoking and a stressful lifestyle are other negative factors affecting IVF outcome.
Can you select the sex of embryo in IVF process?
The advantage of using IVF is that you can use complementary techniques such as pre-implantation genetic diagnosis (PGD) and Microsorting for sex selection. The PGD technique helps couples who have a genetic disorder and give an opportunity to have a normal baby.
What are the pre-IVF assessments?
The couples who are undergoing IVF treatments, they should have a more precise evaluation. The evaluations are as follows:
- Ovarian Reserve test: This test is valuable in predicting the response to induction ovulation drugs and may help the treatment plan.
- Sperm analysis: This test can be used to analyses the number, shape, and motility of sperm. This test should be performed shortly before the treatment to obtain more accurate results. According to the result of this test, the doctor will decide whether to use IVF or ICSI for the egg fertilization.
- Screening for infectious diseases: This test examines both infectious and viral diseases in men and women to ensure the safety of the medical staff and laboratory personnel. In addition, this screening test can protect the IVF embryos against such infections.
- Experimental transfer: This test selects the method of embryo transfer and identifies the women who have difficulty in the embryo transfer process.
- Imaging the uterine cavity: Uterine imaging is performed to ensure the uterus is ready for implantation of the embryo a short time after the start of the treatment cycle. This method can detect the embryo implantation disorder and adverse effect on pregnancy.
The post-treatment care in IVF
In general, the following instructions are advised for the posts IVF periods:
- Regular consumption of medications
- Avoid tense physical activity and exercise until 72 hours after the embryo transfer( daily activities are allowed)
- Do not use the bathtub or vaginal douche
- Avoid sexual intercourse for up to two weeks after the embryo transfer
- Avoid smoking and alcohol consumption
What are the chances of multiple pregnancies in IVF?
The rates of multiple pregnancies following IVF remain high. The mother’s age and the number of embryos to transfer in IVF are the factors that lead to multiple pregnancies in IVF cycles.
The following table shows the percentage of single and multiple births in women fewer than 35 years old, depending on the number of embryos transferred during the IVF treatment process.
IVF cost in Iran
The IVF Costs in Iran (including all surgical and diagnostic procedures, test and treatments) normally ranges between ….. To $ per cycle. On average, the cost of a one-time IVF cycle in the United States is about $15,000, which does not cover the cost of medications. The cost of IVF in Iran is more affordable than other countries. Also, in Iran, the infertility treatments services such as IVF have a high quality in the region and in the world. The low-cost of IVF in Iran is due to the low doctors’ wages and inexpensive services in the clinic. The medications cost are the same all over the world.